Biodefense in the Intelligence Age

OpenAI

An action plan for AI-powered biological resilience

Advanced AI capabilities for biology are improving rapidly and becoming increasingly available across the scientific ecosystem. In April 2026, OpenAI introduced GPT‑Rosalind⁠, our frontier reasoning model built to support research across biology, drug discovery, and translational medicine. We believe advanced AI can help scientists better understand biology, develop new therapies, and improve human health across a wide range of diseases—and Rosalind is a reflection of our commitment to achieve transformational impact that improves health outcomes.

But the same capabilities that can help scientists better understand disease, develop new therapies, and improve human health also have implications for biological security. In May 2026, we announced Rosalind Biodefense⁠ to help trusted developers to build new biodefense and pandemic preparedness capabilities. We believe the best way to strengthen biological security is to equip responsible defenders with advanced capabilities while developing the safeguards, evidence, and governance needed for their safe deployment.

OpenAI is launching this biodefense action plan to help build a more resilient biological future: one in which societies can detect threats sooner, develop countermeasures more rapidly, and respond to crises with greater confidence and coordination.